{"symbol":"EPCAM","synonyms":["HNPCC8","DIAR5","KS1/4","MK-1","EGP-2","EGP314","M4S1","TACSTD1","KSA","EGP40","TROP1","MIC18"],"name":"epithelial cell adhesion molecule","description":"This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]","ncbiEntrezGeneId":4072,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4072","proteins":[{"symbol":"EPCAM_HUMAN","href":"/api/1.0/protein/EPCAM_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}