{"symbol":"EPS15","synonyms":["AF1P","MLLT5","AF-1P"],"name":"epidermal growth factor receptor pathway substrate 15","description":"This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]","ncbiEntrezGeneId":2060,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2060","proteins":[{"symbol":"EPS15_HUMAN","href":"/api/1.0/protein/EPS15_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}