{"symbol":"ERAP2","synonyms":["LRAP","L-RAP"],"name":"endoplasmic reticulum aminopeptidase 2","description":"This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]","ncbiEntrezGeneId":64167,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/64167","proteins":[{"symbol":"ERAP2_HUMAN","href":"/api/1.0/protein/ERAP2_HUMAN"}],"hgncRootFamilies":[{"name":"Aminopeptidases","href":"/api/1.0/gene_family/Aminopeptidases"}]}