{"symbol":"ETV6","synonyms":["TEL/ABL","TEL","THC5"],"name":"ets variant 6","description":"This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]","ncbiEntrezGeneId":2120,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2120","proteins":[{"symbol":"ETV6_HUMAN","href":"/api/1.0/protein/ETV6_HUMAN"}],"hgncRootFamilies":[{"name":"Helix-turn-helix ETS type domain containing","href":"/api/1.0/gene_family/Helix-turn-helix+ETS+type+domain+containing"}]}