{"symbol":"EVX2","synonyms":["EVX-2"],"name":"even-skipped homeobox 2","description":"This gene is located at the 5\u0027 end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5\u0027 end of the HOXD gene cluster, which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease resulting in limb malformation. [provided by RefSeq, Sep 2009]","ncbiEntrezGeneId":344191,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/344191","proteins":[{"symbol":"EVX2_HUMAN","href":"/api/1.0/protein/EVX2_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"}]}