{"symbol":"EXO5","synonyms":["DEM1","HEXO5","EXO V","C1ORF176"],"name":"exonuclease 5","description":"The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5\u0027-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. [provided by RefSeq, Nov 2016]","ncbiEntrezGeneId":64789,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/64789","proteins":[{"symbol":"EXO5_HUMAN","href":"/api/1.0/protein/EXO5_HUMAN"}],"hgncRootFamilies":[{"name":"Exonucleases","href":"/api/1.0/gene_family/Exonucleases"}]}