{"symbol":"EXOC8","synonyms":["EXO84","EXO84P","SEC84"],"name":"exocyst complex component 8","description":"This gene encodes a component of the exocyst complex, an evolutionarily conserved multi-protein complex that plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. This protein is a target of activated Ral subfamily of GTPases and thereby regulates exocytosis by tethering vesicles to the plasma membrane. Mutations in this gene may be related to Joubert syndrome. [provided by RefSeq, Sep 2016]","ncbiEntrezGeneId":149371,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/149371","proteins":[{"symbol":"EXOC8_HUMAN","href":"/api/1.0/protein/EXOC8_HUMAN"}],"hgncRootFamilies":[]}