{"symbol":"EXOSC1","synonyms":["CGI-108","CSL4","CSL4P","SKI4","SKI4P","HCSL4P"],"name":"exosome component 1","description":"This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]","ncbiEntrezGeneId":51013,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51013","proteins":[{"symbol":"EXOS1_HUMAN","href":"/api/1.0/protein/EXOS1_HUMAN"}],"hgncRootFamilies":[{"name":"Exosome components (EXOSC)","href":"/api/1.0/gene_family/Exosome+components+%28EXOSC%29"}]}