{"symbol":"EYA3","synonyms":[],"name":"EYA transcriptional coactivator and phosphatase 3","description":"This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3\u0027 UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]","ncbiEntrezGeneId":2140,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2140","proteins":[{"symbol":"EYA3_HUMAN","href":"/api/1.0/protein/EYA3_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphatases","href":"/api/1.0/gene_family/Phosphatases"}]}