{"symbol":"EZH1","synonyms":["KMT6B"],"name":"enhancer of zeste 1 polycomb repressive complex 2 subunit","description":"EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM, Mar 2009]","ncbiEntrezGeneId":2145,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2145","proteins":[{"symbol":"EZH1_HUMAN","href":"/api/1.0/protein/EZH1_HUMAN"}],"hgncRootFamilies":[{"name":"SANT/Myb domain containing","href":"/api/1.0/gene_family/SANT%24slash%24Myb+domain+containing"},{"name":"Chromatin-modifying enzymes","href":"/api/1.0/gene_family/Chromatin-modifying+enzymes"}]}