{"symbol":"FA2H","synonyms":["SPG35","FAAH","FAH1","FAXDC1","SCS7"],"name":"fatty acid 2-hydroxylase","description":"This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.[provided by RefSeq, Mar 2010]","ncbiEntrezGeneId":79152,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79152","proteins":[{"symbol":"FA2H_HUMAN","href":"/api/1.0/protein/FA2H_HUMAN"}],"hgncRootFamilies":[{"name":"Fatty acid hydroxylase domain containing","href":"/api/1.0/gene_family/Fatty+acid+hydroxylase+domain+containing"}]}