{"symbol":"FBXL19","synonyms":["JHDM1C","FBL19","CXXC11"],"name":"F-box and leucine-rich repeat protein 19","description":"This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]","ncbiEntrezGeneId":54620,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54620","proteins":[{"symbol":"FXL19_HUMAN","href":"/api/1.0/protein/FXL19_HUMAN"}],"hgncRootFamilies":[{"name":"F-boxes (FBX)","href":"/api/1.0/gene_family/F-boxes+%28FBX%29"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}