{"symbol":"FBXO17","synonyms":["FBG4","FBX26","FBXO26","FBX17"],"name":"F-box protein 17","description":"This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]","ncbiEntrezGeneId":115290,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/115290","proteins":[{"symbol":"FBX17_HUMAN","href":"/api/1.0/protein/FBX17_HUMAN"}],"hgncRootFamilies":[{"name":"F-boxes (FBX)","href":"/api/1.0/gene_family/F-boxes+%28FBX%29"}]}