{"symbol":"FCGR2B","synonyms":["CD32B","FCGR2C","FcRII-c"],"name":"Fc fragment of IgG, low affinity IIb, receptor (CD32)","description":"The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]","ncbiEntrezGeneId":2213,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2213","proteins":[{"symbol":"FCG2B_HUMAN","href":"/api/1.0/protein/FCG2B_HUMAN"}],"hgncRootFamilies":[{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}