{"symbol":"FCHO1","synonyms":[],"name":"FCH domain only 1","description":"Enables AP-2 adaptor complex binding activity. Involved in several processes, including T cell receptor signaling pathway; clathrin coat assembly; and clathrin-dependent endocytosis. Located in cytosol; nucleoplasm; and plasma membrane. Is active in clathrin-coated pit. Implicated in primary immunodeficiency disease. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":23149,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23149","proteins":[{"symbol":"FCHO1_HUMAN","href":"/api/1.0/protein/FCHO1_HUMAN"}],"hgncRootFamilies":[]}