{"symbol":"FCN1","synonyms":["FCNM"],"name":"ficolin (collagen/fibrinogen domain containing) 1","description":" The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins.  However, all these proteins recognize different targets, and are functionally distinct.  Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":2219,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2219","proteins":[{"symbol":"FCN1_HUMAN","href":"/api/1.0/protein/FCN1_HUMAN"}],"hgncRootFamilies":[{"name":"Fibrinogen C domain containing","href":"/api/1.0/gene_family/Fibrinogen+C+domain+containing"}]}