{"symbol":"FERMT2","synonyms":["mig-2","UNC112","PLEKHC1","UNC112B","MIG2","KIND2"],"name":"fermitin family member 2","description":"Enables several functions, including phosphatidylinositol-3,4,5-trisphosphate binding activity; protein serine/threonine kinase binding activity; and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of cellular component biogenesis; and positive regulation of intracellular signal transduction. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in several cellular components, including adherens junction; cytoplasmic side of plasma membrane; and focal adhesion. Biomarker of acute myeloid leukemia. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":10979,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10979","proteins":[{"symbol":"FERM2_HUMAN","href":"/api/1.0/protein/FERM2_HUMAN"}],"hgncRootFamilies":[{"name":"Pleckstrin homology domain containing (PLEKH)","href":"/api/1.0/gene_family/Pleckstrin+homology+domain+containing+%28PLEKH%29"}]}