{"symbol":"FGD5","synonyms":["ZFYVE23"],"name":"FYVE, RhoGEF and PH domain containing 5","description":"Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization; filopodium assembly; and regulation of cell shape. Located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":152273,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/152273","proteins":[{"symbol":"FGD5_HUMAN","href":"/api/1.0/protein/FGD5_HUMAN"}],"hgncRootFamilies":[{"name":"Pleckstrin homology domain containing (PLEKH)","href":"/api/1.0/gene_family/Pleckstrin+homology+domain+containing+%28PLEKH%29"},{"name":"Rho guanine nucleotide exchange factors (ARHGEF)","href":"/api/1.0/gene_family/Rho+guanine+nucleotide+exchange+factors+%28ARHGEF%29"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}