{"symbol":"FGF1","synonyms":["AFGF","ECGFB","ECGF-BETA","FGFA","FGF-1","ECGFA","HBGF-1","FGF-ALPHA","HBGF1","GLIO703"],"name":"fibroblast growth factor 1 (acidic)","description":"The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]","ncbiEntrezGeneId":2246,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2246","proteins":[{"symbol":"FGF1_HUMAN","href":"/api/1.0/protein/FGF1_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"}]}