{"symbol":"FGF23","synonyms":["HPDR2","PHPTC","HFTC2","FGFN"],"name":"fibroblast growth factor 23","description":"This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]","ncbiEntrezGeneId":8074,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8074","proteins":[{"symbol":"FGF23_HUMAN","href":"/api/1.0/protein/FGF23_HUMAN"}],"hgncRootFamilies":[]}