{"symbol":"FHL2","synonyms":["FHL-2","DRAL","SLIM-3","AAG11","SLIM3"],"name":"four and a half LIM domains 2","description":"This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2016]","ncbiEntrezGeneId":2274,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2274","proteins":[{"symbol":"FHL2_HUMAN","href":"/api/1.0/protein/FHL2_HUMAN"}],"hgncRootFamilies":[]}