{"symbol":"FKBP1B","synonyms":["FKBP1L","FKBP12.6","OTK4","PKBP1L"],"name":"FK506 binding protein 1B, 12.6 kDa","description":"The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":2281,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2281","proteins":[{"symbol":"FKB1B_HUMAN","href":"/api/1.0/protein/FKB1B_HUMAN"}],"hgncRootFamilies":[{"name":"Peptidylprolyl isomerases","href":"/api/1.0/gene_family/Peptidylprolyl+isomerases"}]}