{"symbol":"FKBP3","synonyms":["FKBP25","FKBP-3","FKBP-25"],"name":"FK506 binding protein 3, 25kDa","description":"The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]","ncbiEntrezGeneId":2287,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2287","proteins":[{"symbol":"FKBP3_HUMAN","href":"/api/1.0/protein/FKBP3_HUMAN"}],"hgncRootFamilies":[{"name":"Peptidylprolyl isomerases","href":"/api/1.0/gene_family/Peptidylprolyl+isomerases"}]}