{"symbol":"FMO4","synonyms":["FMO2"],"name":"flavin containing monooxygenase 4","description":"Metabolic N-oxidation of diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man. This results in a small subpopulation with reduced TMA N-oxidation capacity and causes fish odor syndrome (Trimethylaminuria). Three forms of the enzyme are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Jan 2015]","ncbiEntrezGeneId":2329,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2329","proteins":[{"symbol":"FMO4_HUMAN","href":"/api/1.0/protein/FMO4_HUMAN"}],"hgncRootFamilies":[]}