{"symbol":"FNIP1","synonyms":[],"name":"folliculin interacting protein 1","description":"This gene encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]","ncbiEntrezGeneId":96459,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/96459","proteins":[{"symbol":"FNIP1_HUMAN","href":"/api/1.0/protein/FNIP1_HUMAN"}],"hgncRootFamilies":[{"name":"DENN/MADD domain containing (DENND)","href":"/api/1.0/gene_family/DENN%24slash%24MADD+domain+containing+%28DENND%29"}]}