{"symbol":"FOS","synonyms":["C-FOS"],"name":"FBJ murine osteosarcoma viral oncogene homolog","description":"The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2.  These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.  As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.  In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":2353,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2353","proteins":[{"symbol":"FOS_HUMAN","href":"/api/1.0/protein/FOS_HUMAN"}],"hgncRootFamilies":[{"name":"Basic leucine zipper proteins","href":"/api/1.0/gene_family/Basic+leucine+zipper+proteins"}]}