{"symbol":"FOXC1","synonyms":["IHG1","FKHL7","IRID1","FREAC-3","IGDA","FREAC3","RIEG3","ASGD3"],"name":"forkhead box C1","description":"This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain.  The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development.  Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":2296,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2296","proteins":[{"symbol":"FOXC1_HUMAN","href":"/api/1.0/protein/FOXC1_HUMAN"}],"hgncRootFamilies":[{"name":"Forkhead boxes (FOX)","href":"/api/1.0/gene_family/Forkhead+boxes+%28FOX%29"}]}