{"symbol":"FOXO4","synonyms":["AFX","MLLT7","AFX1"],"name":"forkhead box O4","description":"This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]","ncbiEntrezGeneId":4303,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4303","proteins":[{"symbol":"FOXO4_HUMAN","href":"/api/1.0/protein/FOXO4_HUMAN"}],"hgncRootFamilies":[{"name":"Forkhead boxes (FOX)","href":"/api/1.0/gene_family/Forkhead+boxes+%28FOX%29"}]}