{"symbol":"FREM2","synonyms":["FRASRS2"],"name":"FRAS1 related extracellular matrix protein 2","description":"This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Apr 2014]","ncbiEntrezGeneId":341640,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/341640","proteins":[{"symbol":"FREM2_HUMAN","href":"/api/1.0/protein/FREM2_HUMAN"}],"hgncRootFamilies":[]}