{"symbol":"FSCN1","synonyms":["FAN1","HSN","SNL"],"name":"fascin actin-bundling protein 1","description":"This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin\u0027s lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]","ncbiEntrezGeneId":6624,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6624","proteins":[{"symbol":"FSCN1_HUMAN","href":"/api/1.0/protein/FSCN1_HUMAN"}],"hgncRootFamilies":[{"name":"Fascins (FSCN)","href":"/api/1.0/gene_family/Fascins+%28FSCN%29"}]}