{"symbol":"FZD1","synonyms":[],"name":"frizzled class receptor 1","description":" Members of the \u0027frizzled\u0027 gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.  The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.  The FZD1 transcript is expressed in various tissues. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":8321,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8321","proteins":[{"symbol":"FZD1_HUMAN","href":"/api/1.0/protein/FZD1_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}