{"symbol":"GAB3","synonyms":[],"name":"GRB2-associated binding protein 3","description":"This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]","ncbiEntrezGeneId":139716,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/139716","proteins":[{"symbol":"GAB3_HUMAN","href":"/api/1.0/protein/GAB3_HUMAN"}],"hgncRootFamilies":[{"name":"Pleckstrin homology domain containing (PLEKH)","href":"/api/1.0/gene_family/Pleckstrin+homology+domain+containing+%28PLEKH%29"}]}