{"symbol":"GABRA5","synonyms":[],"name":"gamma-aminobutyric acid (GABA) A receptor, alpha 5","description":"GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":2558,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2558","proteins":[{"symbol":"GBRA5_HUMAN","href":"/api/1.0/protein/GBRA5_HUMAN"}],"hgncRootFamilies":[{"name":"Gamma-aminobutyric acid (GABA) receptors","href":"/api/1.0/gene_family/Gamma-aminobutyric+acid+%28GABA%29+receptors"},{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}