{"symbol":"GALNT12","synonyms":["GALNAC-T12","CRCS1"],"name":"polypeptide N-acetylgalactosaminyltransferase 12","description":"This gene encodes a member of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases, which catalyze the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to a serine or threonine residue on a polypeptide acceptor in the initial step of O-linked protein glycosylation. Mutations in this gene are associated with an increased susceptibility to colorectal cancer.[provided by RefSeq, Mar 2011]","ncbiEntrezGeneId":79695,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79695","proteins":[{"symbol":"GLT12_HUMAN","href":"/api/1.0/protein/GLT12_HUMAN"}],"hgncRootFamilies":[{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"}]}