{"symbol":"GCHFR","synonyms":["GFRP","HST16933"],"name":"GTP cyclohydrolase I feedback regulator","description":"GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":2644,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2644","proteins":[{"symbol":"GFRP_HUMAN","href":"/api/1.0/protein/GFRP_HUMAN"}],"hgncRootFamilies":[]}