{"symbol":"GCNT2","synonyms":["CTRCT13","CCAT","IGNT","GCNT2C","ULG3","NACGT1","BA421M1.1","GCNT5","NAGCT1","BA360O19.2"],"name":"glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)","description":"This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":2651,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2651","proteins":[{"symbol":"GNT2B_HUMAN","href":"/api/1.0/protein/GNT2B_HUMAN"}],"hgncRootFamilies":[{"name":"Blood group antigens","href":"/api/1.0/gene_family/Blood+group+antigens"},{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"}]}