{"symbol":"GDF11","synonyms":["BMP-11","BMP11"],"name":"growth differentiation factor 11","description":"This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]","ncbiEntrezGeneId":10220,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10220","proteins":[{"symbol":"GDF11_HUMAN","href":"/api/1.0/protein/GDF11_HUMAN"}],"hgncRootFamilies":[]}