{"symbol":"GFAP","synonyms":["ALXDRD"],"name":"glial fibrillary acidic protein","description":"This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]","ncbiEntrezGeneId":2670,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2670","proteins":[{"symbol":"GFAP_HUMAN","href":"/api/1.0/protein/GFAP_HUMAN"}],"hgncRootFamilies":[{"name":"Intermediate filaments","href":"/api/1.0/gene_family/Intermediate+filaments"}]}