{"symbol":"GGA2","synonyms":["VEAR"],"name":"golgi-associated, gamma adaptin ear containing, ARF binding protein 2","description":"This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":23062,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23062","proteins":[{"symbol":"GGA2_HUMAN","href":"/api/1.0/protein/GGA2_HUMAN"}],"hgncRootFamilies":[]}