{"symbol":"GGA3","synonyms":[],"name":"golgi-associated, gamma adaptin ear containing, ARF binding protein 3","description":"This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]","ncbiEntrezGeneId":23163,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23163","proteins":[{"symbol":"GGA3_HUMAN","href":"/api/1.0/protein/GGA3_HUMAN"}],"hgncRootFamilies":[]}