{"symbol":"GGCT","synonyms":["GCTG","GGC","CRF21","C7ORF24"],"name":"gamma-glutamylcyclotransferase","description":"The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]","ncbiEntrezGeneId":79017,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79017","proteins":[{"symbol":"GGCT_HUMAN","href":"/api/1.0/protein/GGCT_HUMAN"}],"hgncRootFamilies":[]}