{"symbol":"GGTLC3","synonyms":[],"name":"gamma-glutamyltransferase light chain 3","description":"Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC3, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]","ncbiEntrezGeneId":728226,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/728226","proteins":[{"symbol":"GGTL3_HUMAN","href":"/api/1.0/protein/GGTL3_HUMAN"}],"hgncRootFamilies":[{"name":"Gamma-glutamyltransferases (GGT)","href":"/api/1.0/gene_family/Gamma-glutamyltransferases+%28GGT%29"}]}