{"symbol":"GJA8","synonyms":["MP70","CX50","CAE1","CAE","CZP1","CTRCT1"],"name":"gap junction protein, alpha 8, 50kDa","description":"This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009]","ncbiEntrezGeneId":2703,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2703","proteins":[{"symbol":"CXA8_HUMAN","href":"/api/1.0/protein/CXA8_HUMAN"}],"hgncRootFamilies":[{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}