{"symbol":"GLRX3","synonyms":["GRX4","TXNL3","GRX3","TXNL2","PICOT","GLRX4"],"name":"glutaredoxin 3","description":"This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]","ncbiEntrezGeneId":10539,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10539","proteins":[{"symbol":"GLRX3_HUMAN","href":"/api/1.0/protein/GLRX3_HUMAN"}],"hgncRootFamilies":[]}