{"symbol":"GNB1","synonyms":["MRD42"],"name":"guanine nucleotide binding protein (G protein), beta polypeptide 1","description":"Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]","ncbiEntrezGeneId":2782,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2782","proteins":[{"symbol":"GBB1_HUMAN","href":"/api/1.0/protein/GBB1_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}