{"symbol":"GNRH1","synonyms":["GNRH","GRH","LHRH","HH12","LNRH"],"name":"gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)","description":"This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]","ncbiEntrezGeneId":2796,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2796","proteins":[{"symbol":"GON1_HUMAN","href":"/api/1.0/protein/GON1_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"}]}