{"symbol":"GPR27","synonyms":["SREB1"],"name":"G protein-coupled receptor 27","description":"GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins.[supplied by OMIM, May 2010]","ncbiEntrezGeneId":2850,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2850","proteins":[{"symbol":"GPR27_HUMAN","href":"/api/1.0/protein/GPR27_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}