{"symbol":"GPR3","synonyms":["ACCA"],"name":"G protein-coupled receptor 3","description":"This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer\u0027s disease. [provided by RefSeq, Oct 2012]","ncbiEntrezGeneId":2827,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2827","proteins":[{"symbol":"GPR3_HUMAN","href":"/api/1.0/protein/GPR3_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}