{"symbol":"GPR85","synonyms":["SREB","SREB2"],"name":"G protein-coupled receptor 85","description":"Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]","ncbiEntrezGeneId":54329,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54329","proteins":[{"symbol":"GPR85_HUMAN","href":"/api/1.0/protein/GPR85_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}