{"symbol":"GRB7","synonyms":[],"name":"growth factor receptor-bound protein 7","description":"The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]","ncbiEntrezGeneId":2886,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2886","proteins":[{"symbol":"GRB7_HUMAN","href":"/api/1.0/protein/GRB7_HUMAN"}],"hgncRootFamilies":[{"name":"SH2 domain containing","href":"/api/1.0/gene_family/SH2+domain+containing"},{"name":"Pleckstrin homology domain containing (PLEKH)","href":"/api/1.0/gene_family/Pleckstrin+homology+domain+containing+%28PLEKH%29"}]}